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Hereditary Neuropathy with Liability to Pressure Palsy (HNPP) is a peripheral neuropathy (disorder of the nerves). ==General description== HNPP is a nerve disorder that affects the peripheral nerves. The main effect of HNPP are pressure palsies. Pressure on the nerves can cause tingling sensations, numbness, pain, weakness, muscle atrophy, and even paralyzation of affected area. In normal individuals these symptoms disappear quickly but in sufferers of HNPP even a short period of pressure can cause the symptoms to occur. These usually subside over an extended period of time. Palsies can last from minutes, day to weeks or even months or years. However repeated incidents can cause permanent muscle weakness. HNPP evolves slowly with symptoms surfacing between usually in the late teens to early twenties (range 8 to 64 years). The symptoms vary from person to person. Some report minor problems, whilst others experience severe discomfort and a moderate disability. In many cases the symptoms are mild enough to go unnoticed. The time period between episodes is known to vary between individuals. HNPP has not been found to alter the lifespan, although in some cases a decline in quality of life is noticed. Some sufferers (10-15%) report various pains growing in severity with progression of the disease.〔(【引用サイトリンク】url=http://ghr.nlm.nih.gov/condition/hereditary-neuropathy-with-liability-to-pressure-palsies )〕 The nerves most commonly affected are the peroneal nerve at the fibular head (leg and feet), the ulnar nerve at the elbow (arm) and the median nerve at the wrist (palm, thumbs and fingers). HNPP is part of the group of Hereditary Motor and Sensory Neuropathy (HMSN) and is linked to Charcot–Marie–Tooth disease (CMT). 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Hereditary neuropathy with liability to pressure palsy」の詳細全文を読む スポンサード リンク
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